2^nd Global Experts Meeting on Chronic Diseases October 23-24, 2019 Tokyo, Japan

Biography:

Alonge has completed his Master’s degree in 2012  from the University  of Yaounde 1. He is a lecturer in the school of laboratory technicians in Yaounde Cameroon and is looking forward to completing his PhD in Microbiology.  He has assumed the leadership role in research in Helicobacter pylori and gastritis. He has published more  7papers  papers and 1 book in reputed journals. 

Abstract:

Background:  Human Immunodeficiency virus (HIV) and Helicobacter pylori(H. pylori)are associated with significant d chronic inflammation of the gastric mucosa. Gastric inflammation is a precursor to many gastrointestinal disorders including, peptic ulcer, atrophic gastritis (AG) and gastric cancer (GC). AGis usually accompanied by low hydrochloric acid(hypochlorhydria), low pepsinogens (PG) and high gastrin (G) levels and is the most  significant risk condition for GC. Acid-free stomach  is a risk factor for impaired drug absorption including anti-retroviral therapy and antibiotics. We assessed  the prevalence of H. pylori infection, AG and acid-free stomach (hypochlorhydria) amongst HIV/AIDS subjects in Cameroon.

Methods: 84 HIV/AIDS subjects were recruited in Yaounde during January-May 2018. Clinical and socio-demographic data  of the subjectswere recorded. 5 ml of blood was aseptically collected for analysis by GastroPanel® biomarker test for PGI, PGII,G-17 and H.pylori IgG antibodies. GastroPanel results were interpreted using the software application GastroSoft® (Biohit). Statistical analyses were run by Epi info 7.0. 

Results: 84 subjects were recruited,aged  between17-63 years(mean 37.6 ± 8.9 years). H. pylori seropositivity (IgG ≥30 EIU) was detected in 68(81.0%) of the subjects. H. pylori seropositivity was closely associated with low CD4 counts (p=0.01). Altogether, 26(31.0%) of the subjects presented with AG of  the corpus, while, hypochlorhydria (acid-free stomach) was detected in 32(38.1%) of the patients.  AG and hypochlorhydria were associated with low CD4 counts<200μl/l (p=0.01) and (p=0.005), respectively.

Conclusion: H. pylori infection, AG and acid-free stomach were common among HIV/AIDS patients, associated with  an increased risk for GC and impaired absorption of micronutrients and some medicines.

Biography:

Leire Ambrosio has completed her PhD in Nursing at the age of 25 years from University of Navarra, with the extraordinary doctoral award. She is the coordinator of the ReNACE Program, a larger, multidisciplinary, and international research programme. She is leading a multidisciplinary and national proyect focused on living with chronic illness granted by the Ministry of Economy and Competitiveness in Spain. Besides, is working with international teams expanding the EC-PC in the UK and across Europe and Latin America, and building strong links between sectors to promote a positive living and management of chronic diseases.

Abstract:

Incidence and prevalence of chronic diseases have suffered a significant increase in today's society, due to demographic changes occurring in the population structure in the 20th century in all over the world. According to the official report established by the World Health Organization, in depth understanding of how the person lives with a chronic illness is paramount to provide holistic and quality care, according to the specific demands of each person. In this respect, the use of clinical instruments that allow to asses and gain knowledge on the process of living with a chronic illness, from the patient's perspective, is strongly advocated. At present, the Living with Chronic Illness Scale (EC-PC, from Escala de Convivenca con un Proceso Crónico) is the only measurement tool that evaluates how the patient is living with a chronic illness from a holistic perspective. The EC-PC is an innovative clinical measure that evaluates the degree of living with a chronic illness form the patient perspective. The EC-PC is been validated  in a population with different, prototypical and high prevalence chronic illnesses in nowadays society such as, Parkinson’s disease, diabetes mellitus type 2, chronic heart failure, COPD, osteoarthritis or arterial hypertension. This will allow concluding whether the EC-PC is a valid and reliable scale to measure the degree of living with a chronic illness, and consequently, to be used in clinical setting. In this way, health and social care professionals will be able to design individualized interventions, according to the specific needs of each person.

Biography:

Amir Nawaz, Department of Microbiology, Government College University Faisalabad, Pakistan

Abstract:

Hatching eggs risk of contamination starts right from the point of lay as they are at risk by external contamination through the pores and hairline cracks in the shell, vertical transmission from infected flocks, vectors such as hands, trays, vermin, transport equipment. For this study, we dealed with eggs of different breeder flocks of variable age. Total of 500 samples of breeder eggs that were received at hatchery from breeder farms as well as samples of day old chicks hatched after 21 days of incubation from similar batches of fertile eggs. We took these samples of eggs that were sub divided according to mobility of eggs. Contamination in incubators had also been checked during first 18 days of incubation as multistage incubators facilitate the incubation of microbes as well during the incubation of eggs. Normal eggs as well as from exploder had also been checked and their cause of exploding where multi aged eggs incubated together, after incubation of 18 days we went after the risk of contamination in transfer area from setter to hatchers. All collected samples were sub cultured on blood MacConkey agar and incubated at 37°C overnight. Colonies were identified on the basis of culture morphology and colony characteristic. Bacterial confirmation had been done using API20E and 20NE. Antimicrobial susceptibility testing performed by using Kirby Bauer disc diffusion method according to CLSI 2016 guidelines. The data had analyzed using SPSS 25 version. We found that the E. coli are the most prevalent isolated microorganism (100%, (SP 112 Hatcher), 75% (SP 117 Hatcher) and 50% (SP 119 Hatcher, AP 27 Hatcher and SS 02 Setter) followed by Enterococcus spp., 62.5% (SP 119 Setter) and Staphylococcus species considered as commensals. We found the hatcher area overall more contaminated as compared to other isolation site (p < 0.05). However, Proteus spp., (100%, 100% and 100%) followed by Enterococcus Spp., (100%, 100% and 100%) and salmonella spp., (80%, 100% and 100%) are the most resistance to penicillin class followed by aminoglycoside and carbapenem class respectively (p < 0.05).

Biography:

Lijuan Xuan, Sichuan University, China

Abstract:

Background: Heart failure(HF) is the end stage of many cardiovascular diseases, which incurs a high prevalence, mortality and morbidity. An increasing number of studies showed that about 30% of the HF patients were readmitted within 30 days after discharge due to the clinical exacerbation. Recurrent hospitalizations not only worsen the heart function, but also increase the healthcare costs. Researchers have reported that high level of readiness for hospital discharge can lower the readmission rate. In addition, quality of discharge teaching(QDT) has emerged as a momentous factor influencing the readiness for hospital discharge(RHD). However, there is little research on the status of RHD and its association with the QDT in HF patients. Objective: The purpose of this study is to assess readiness for discharge and explore its correlation with the QDT in HF patients. Method: This is a cross-sectional study and a convenience sample of 160 patients were selected according to the inclusion criterions. Results: There were 88.8% (n=142) patients who were ready for discharge. The average scores of the readiness of discharge and the QDT were respectively (7.47±1.16) and (7.32±1.36). The scores of the RHD sub-scales from high to low were expected support (7.80±1.51), personal status (7.54±1.47), coping ability (7.48±1.66) and knowledge (7.27±1.57). There was positive correlation between the readiness of discharge and QDT in HF patients (r=0.457, P＜0.01). Conclusion: The RHD in HF patients presented in a medium level. There was positive correlation between readiness of discharge and QDT. Important consideration should be given to patient education and the training on discharge teaching skills also recommended for medical staff.